Isotretinoin Accutane is an anti-acne drug chemically bound to retinoic acid and retinol (vitamin A). The exact mechanism of action is not known, it blocks the sebaceous glands, reduces the production of fat in the skin, and thereby prevents the development of acne. It is sold in many countries around the world and is considered one of the most effective ways to combat acne. In a recent study, 160 volunteers used Accutane for 2-28 weeks. Of the 133 patients who remained at the end of the experiment, 127 patients noted the complete or almost complete disappearance of acne. That is 95% efficiency, which is very important for any drug. Also, 60% of patients have not worried about acne for another year after the end of taking Accutane. Bodybuilders use it for the same purpose to remove one of the most noticeable external side effects of consuming AAS.
Isotretinoin Accutane was developed by Hoffmann-La Roche, and was first released to the market in 1982. It was sold until 2002 under the patent name Accutane. Now he is on the market under a variety of names. Isotretinoin is an approved drug, but in recent years its sale has been regulated due to side effects. In particular, women need to make sure that they are not pregnant. The drug carries yellow stickers listing possible side effects.
Isotretinoin Accutane is usually available in the form of gelatin capsules containing 10.20 or 40mg of the drug.
Isotretinoin is a derivative of retinoic acid, 13-cis-retinoic acid.
Isotretinoin is a powerful drug with corresponding side effects. This is a controversial drug. At one time, newspapers rattled about him, that he could cause fetal defects, depression, and cause suicide. Reception during pregnancy can cause serious complications in the development of the fetus. It is also somewhat hepatotoxic, can cause intestinal inflammation, pancreatitis, suppress good cholesterol and impair hearing and eyesight, can also cause psychosis, palpitations, hoarseness, increased intracranial pressure and even deformity of the nasal cartilage if taken after surgery at this place.
Although it is not precisely proven that Accutane can cause depression, psychosis, and suicidal tendencies, this possibility cannot but be taken seriously.
This opportunity was explored in 2005. 28 people participated in this study, half of them took Accutane, and half one of the modern antibiotics. Computed tomography was performed before and after 4 weeks of drug use. They testified to changes in part of the cerebral cortex, in the area that is responsible for depressive states. Accutane in these areas decreased metabolism by 21%, while those who took antibiotics, only 2%.