Ekovir-800 mg is an antiviral agent from the group of synthetic analogs of the acyclic purine nucleoside – deoxyguanidine, which is a component of DNA. Ekovir-800 has a high specificity for Herpes simplex, type 1 and type 2 viruses, varicella and shingles virus (Varicella zoster), Epstein-Barr virus. Moderately active against cytomegalovirus.
Ekovir-800 penetrates directly into virus-infected cells. Cells infected with the virus produce viral thymidine kinase, which in turn phosphorylates acyclovir to acyclovir triphosphate, which is an active and selective inhibitor of viral DNA polymerase.
Probably, the mechanism of inhibition of DNA synthesis by acyclovir triphosphate is that it is a substrate for this enzyme, allowing for the connection 3-5, necessary for the extension of the DNA chain.
Thus, a premature break of the DNA chain is carried out, which leads to the suppression of virus replication.