EXOS 25 (Exemestane) is a drug group of aromatase inhibitors, which reduces the production of estrogen in the body. It is used on the steroid course to reduce the aromatase effect (conversion of testosterone to estrogen) while taking anabolic hormonal preparations.
Alternative drugs: Letrozole, Anastrozole.
Effects of EXOS (Exemestane)
- Gynecomastia prophylaxis
- Decreased estrogen production (by 97%)
- Increased anabolic hormone levels
- Improved muscle relief
- Prevention of hypertension
- Reduction of estrogen suppression of the hypothalamus-pituitary-testicle axis
Dosage and course of administration EXOS (Exemestane)
For prevention (in bodybuilding): 12.5 mg every other day.
For the treatment of gynecomastia: 25 mg every day until symptoms disappear (12.5 mg every day).
Reception at a course of steroids:
When using steroids with a short half-life (testosterone propionate, methandrostenolone): after 10 days of the course, take an estradiol test and take 12.5 mg EXOS (Exemestane) every other day. Then after 10 days, again test for estradiol and adjust the dosage of EXOS (Exemestane) according to their results.
When using steroids with long esters (enanthate, sustanon, cypionate): after 3-4 weeks of the course, pass tests for estradiol and take 12.5 mg EXOS (Exemestane) every other day. Then after 10 days, again test for estradiol and adjust the dosage of EXOS (Exemestane) according to their results.
Like other aromatase inhibitors, the dosage of EXOS can be adjusted according to subjective sensations. If while taking EXOS (Exemestane) there are depressions, decreased libido and erectile dysfunction, the dosage must be reduced.
EXOS (25 mg) is an irreversible steroid aromatase inhibitor, similar in structure to the natural substance – androstenedione. EXOS does not affect the biosynthesis of cortisol and aldosterone in the adrenal glands, which confirms the selectivity of the drug. In this regard, there is no need for replacement therapy with gluco – and mineralocorticoids.
With a single dose of 12.5 mg, the maximum plasma concentration is 8 ng / ml and is reached after 2 hours. Simultaneous food intake increases the bioavailability of the drug by 40%.
With the use of the drug, even in low doses, there is a slight increase in serum levels of LH and FSH, which is characteristic of drugs of this pharmacological group.